Panagiotis Paliogiannis
University of Sassari
CancerInternal medicineRadiologySurgeryPathologyOncologyOxidative stressCOPDMelanomaLymphocyteNeutrophil to lymphocyte ratioDiseaseMalignancyIn patientIncidence (epidemiology)MutationCancer researchColorectal cancerMedicineBiologyGastroenterologyMeta-analysis
186Publications
19H-index
1,237Citations
Publications 184
Newest
#1Antonella Manca (National Research Council)H-Index: 22
#2Maria Cristina SiniH-Index: 16
Last. Sara Simi (UniFI: University of Florence)H-Index: 2
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Deep penetrating nevi (DPNs) are rare melanocytic neoplasms consisting of pigmented spindled or epithelioid melanocytes with a distinctive wedge-shaped configuration showing activation of the WNT pathway, with unusual cyto-architectural features. It is unclear whether they show a distinct genomic profile associated with a diverse metastatic potential. We describe herein a cohort of 21 atypical DPNs analyzed by next-generation sequencing using the Ion AmpliSeq™ Comprehensive Cancer Panel. We foun...
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Abstract null null Background null Anastomotic leakage (AL) is one of the most severe complications in colorectal surgery. Currently, no predictive biomarkers of AL are available. The aim of this study was to investigate the role of C reactive protein (CRP) to albumin ratio (CAR) as a predictor of AL in patients undergoing elective surgery for colorectal cancer. Materials and Methods. Data on 1183 consecutive patients surgically treated for histologically proven colorectal cancer in the surgical...
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#1Caterina Arru (University of Sassari)H-Index: 1
#2Maria Rosaria De Miglio (University of Sassari)H-Index: 22
Last. Panagiotis Paliogiannis (University of Sassari)H-Index: 19
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Introduction null Cancer immunotherapy represents one of the most important innovations in modern medicine. Durvalumab is an anti-programmed cell death ligand 1 (PDL-1) agent which is currently under investigation in several studies in combination with the anti-cytotoxic T lymphocyte-associated protein 4 (CTLA-4) drug tremelimumab. The aim of this review was to systematically identify and revise the current scientific literature investigating the combination of these two drugs in solid tumors. n...
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#1Giuseppe PalmieriH-Index: 42
#2Carla RozzoH-Index: 17
Last. Antonio CossuH-Index: 32
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The improvement of the immunotherapeutic potential in most human cancers, including melanoma, requires the identification of increasingly detailed molecular features underlying the tumor immune responsiveness and acting as disease-associated biomarkers. In recent past years, the complexity of the immune landscape in cancer tissues is being steadily unveiled with a progressive better understanding of the plethora of actors playing in such a scenario, resulting in histopathology diversification, d...
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#1Angelo Zinellu (University of Sassari)H-Index: 31
#2Panagiotis Paliogiannis (University of Sassari)H-Index: 19
Last. Arduino A. Mangoni (Flinders Medical Centre)H-Index: 40
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Platelets play an important role in the pathophysiology of chronic obstructive pulmonary disease (COPD) by mediating thrombotic, inflammatory, and immune processes in the lung. We conducted a syste...
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#1Angelo Zinellu (University of Sassari)H-Index: 31
#2Andrea De Vito (University of Sassari)H-Index: 5
Last. Alessandro G. Fois (University of Sassari)H-Index: 17
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Introduction The early identification of factors that predict the length of hospital stay (HS) in patients affected by coronavirus desease (COVID-19) might assist therapeutic decisions and patient flow management. Methodology We collected, at the time of admission, routine clinical, laboratory, and imaging parameters of hypoxia, lung damage, inflammation, and organ dysfunction in a consecutive series of 50 COVID-19 patients admitted to the Respiratory Disease and Infectious Disease Units of the ...
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#1Angelo Zinellu (University of Sassari)H-Index: 31
#2Panagiotis Paliogiannis (University of Sassari)H-Index: 19
Last. Arduino A. Mangoni (Flinders Medical Centre)H-Index: 40
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Abstract Background and objectives An excessive inflammatory response in patients with coronavirus disease 2019 (COVID-19) is associated with high disease severity and mortality. Specific acute phase reactants might be useful for risk stratification. We conducted a systematic review and meta-analysis of studies of serum amyloid A (SAA) in patients with COVID-19. Methods We searched PubMed, Web of Science and Scopus, between January 2020 and December 2020, for studies reporting SAA concentrations...
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#1Salvatore SotgiaH-Index: 25
#2Alessandro G. FoisH-Index: 17
Last. Angelo ZinelluH-Index: 31
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This study aimed to review and critically appraise the current methodological issues undermining the suitability of the measurement of serum/plasma glutathione, both in the total and reduced form, as a measure of systemic oxidative stress in chronic obstructive pulmonary disease (COPD). Fourteen relevant articles published between 2001 and 2020, in 2003 subjects, 1111 COPD patients, and 892 controls, were reviewed. Nine studies, in 902 COPD patients and 660 controls, measured glutathione (GSH) i...
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#1Lara J. Bou Malhab (UOS: University of Sharjah)H-Index: 1
#2Maha Saber-Ayad (UOS: University of Sharjah)H-Index: 8
Last. Wael M. Abdel-Rahman (UOS: University of Sharjah)H-Index: 25
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Long-lasting subclinical inflammation is associated with a wide range of human diseases, particularly at middle and older age. Recent reports showed that there is a direct causal link between inflammation and cancer development, as several cancers were found to be associated with chronic inflammatory conditions. In patients with cancer, healthy endothelial cells regulate vascular homeostasis, and it is believed that they can limit tumor growth, invasiveness, and metastasis. Conversely, dysfuncti...
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#2Panagiotis Paliogiannis (University of Sassari)H-Index: 19
Last. Gianfranco Pintus (University of Sassari)H-Index: 32
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Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an abnormal fibrotic response involving vast areas of the lungs. Given the poor knowledge of the mechanisms underpinning IPF onset and progression, a better understanding of the cellular processes and molecular pathways involved is essential for the development of effective therapies, currently lacking. Besides a number of e...
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