Johan Vanhaecke
Katholieke Universiteit Leuven
Internal medicineEndocrinologySurgeryCardiologyRandomized controlled trialIntensive care medicineProspective cohort studyLungHeart rateHeart failureCoronary artery diseaseHeart transplantationLung transplantationTransplantationTransplant patientAnesthesiaMyocardial infarctionMedicineEjection fractionGastroenterology
324Publications
47H-index
7,953Citations
Publications 320
Newest
#1Nathalie Duerinckx (Katholieke Universiteit Leuven)H-Index: 6
#2Patrick Smith (Duke University)H-Index: 71
Last. Fabienne Dobbels (University of Basel)H-Index: 60
view all 8 authors...
Abstract Objective To investigate the impact of depressive symptoms at 1-year post-heart transplant (HTx) on cardiac allograft vasculopathy (CAV) and mortality. Methods We performed a single-center prospective cohort study of patients 1-year post-HTx consecutively enrolled between January 2001 and September 2015, and followed-up until November 2020. Kaplan-Meier and uni- and multivariate cox proportional hazards models were used to investigate the impact of depressive symptoms (Beck Depression I...
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#1Jan Van Keer (Katholieke Universiteit Leuven)H-Index: 8
#2Lucas N.L. Van Aelst (Katholieke Universiteit Leuven)H-Index: 9
Last. Johan Van Cleemput (Katholieke Universiteit Leuven)H-Index: 30
view all 11 authors...
Abstract Background Cardiac allograft vasculopathy (CAV) is a major complication limiting long-term survival after heart transplantation (HTx). However, long-term outcome data of HTx recipients with detailed information on angiographic severity are scarce. Methods The study included 501 HTx recipients with angiographic follow-up up to 20 years post-transplant. All coronary angiograms were classified according to the International Society for Heart and Lung Transplantation (ISHLT) grading scale. ...
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#1Qi-Fang Huang (Katholieke Universiteit Leuven)H-Index: 17
#2Zhenyu Zhang (Katholieke Universiteit Leuven)H-Index: 141
Last. Jan A. Staessen (UM: Maastricht University)H-Index: 138
view all 14 authors...
Background: Chronic kidney disease (CKD) is common in patients after heart transplantation (HTx). We assessed whether in HTx recipients the proteomic urinary classifier CKD273 or sequenced urinary peptides revealing the parental proteins correlated with the estimated glomerular filtration rate (eGFR). Methods: In 368 HTx patients, we measured the urinary peptidome and analysed CKD273 and 48 urinary peptides with a detectable signal in >95% of participants. After 9.1 months (median), eGFR and the...
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#1Qi-Fang HuangH-Index: 17
#2Sander TrensonH-Index: 9
Last. Jan A. StaessenH-Index: 138
view all 16 authors...
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#1Qi-Fang HuangH-Index: 17
#2Jan Van KeerH-Index: 8
Last. Jan A. StaessenH-Index: 138
view all 15 authors...
Source
#1Zhenyu ZhangH-Index: 141
#2Sander TrensonH-Index: 9
Last. Jan A. StaessenH-Index: 138
view all 18 authors...
Source
#1Qi-Fang HuangH-Index: 17
#2Zhenyu ZhangH-Index: 141
Last. Jan A. StaessenH-Index: 138
view all 14 authors...
Source
#1Qi-Fang Huang (Katholieke Universiteit Leuven)H-Index: 17
#2Jan Van Keer (Katholieke Universiteit Leuven)H-Index: 8
Last. Jan A. Staessen (UM: Maastricht University)H-Index: 138
view all 15 authors...
Objectives Heart transplant (HTx) recipients have a high heart rate (HR), because of graft denervation and are frequently started on β-blockade (BB). We assessed whether BB and HR post HTx are associated with a specific urinary proteomic signature. Methods In 336 HTx patients (mean age, 56.8 years; 22.3% women), we analyzed cross-sectional data obtained 7.3 years (median) after HTx. We recorded medication use, measured HR during right heart catheterization, and applied capillary electrophoresis ...
Source
#1Zhenyu Zhang (Katholieke Universiteit Leuven)H-Index: 141
#2Sander Trenson (Katholieke Universiteit Leuven)H-Index: 9
Last. J.A. Staessen (Katholieke Universiteit Leuven)H-Index: 20
view all 15 authors...
Source
#1Bert Vandenberk (Katholieke Universiteit Leuven)H-Index: 16
#2Mark Hinderks (Katholieke Universiteit Leuven)H-Index: 1
Last. Rik Willems (Katholieke Universiteit Leuven)H-Index: 34
view all 6 authors...
Aims: The latest 2015 ESC Guidelines on the prevention of sudden cardiac death make a Class IIa recommendation for ICD implantation in patients listed for heart transplantation. This recommendation was based on expert consensus in view of the sparsity of data. Methods and results: All patients listed for heart transplantation at the University Hospitals of Leuven from 2002 until 2014 were studied retrospectively. Exclusion criteria were age <16 years, cardiac disease other than ischaemic or dila...
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