Liv Veldeman
Ghent University Hospital
Acute toxicityCancerSupine positionInternal medicineRadiologySurgeryOncologyProne positionRandomized controlled trialMedical physicsLung cancerDeep inspiration breath-holdProstate cancerPopulationWhole Breast IrradiationBreast radiotherapyToxicityNuclear medicineRadiation therapyBreast cancerMedicineCohort
85Publications
15H-index
1,034Citations
Publications 83
Newest
#1Bruno Speleers (UGent: Ghent University)H-Index: 13
#2Max Schoepen (UGent: Ghent University)H-Index: 3
Last. Werner De Gersem (UGent: Ghent University)H-Index: 32
view all 15 authors...
We report on a comparative dosimetrical study between deep inspiration breath hold (DIBH) and shallow breathing (SB) in prone crawl position for photon and proton radiotherapy of whole breast (WB) and locoregional lymph node regions, including the internal mammary chain (LN_MI). We investigate the dosimetrical effects of DIBH in prone crawl position on organs-at-risk for both photon and proton plans. For each modality, we further estimate the effects of lung and heart doses on the mortality risk...
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#1Vincent Vakaet (UGent: Ghent University)H-Index: 2
#2Hans Van Hulle (UGent: Ghent University)H-Index: 2
Last. Liv Veldeman (UGent: Ghent University)H-Index: 15
view all 11 authors...
Abstract Background and purpose Deep inspiration breath-hold is an established technique to reduce heart dose during breast cancer radiotherapy. However, modern breast cancer radiotherapy techniques with lymph node irradiation often require long beam-on times of up to 5 minutes. Therefore, the combination with deep inspiration breath-hold (DIBH) becomes challenging. A simple support technique for longer duration deep inspiration breath-hold (L-DIBH), feasible for daily use at the radiotherapy de...
1 CitationsSource
#1Hans Van Hulle (UGent: Ghent University)H-Index: 2
#2Eline Desaunois (UGent: Ghent University)
Last. Liv Veldeman (UGent: Ghent University)H-Index: 15
view all 13 authors...
Abstract Introduction A simultaneous integrated boost (SIB) leads to less acute toxicity. Less is known for late toxicity due to SIB. In this first and only randomized trial, two-years toxicity is analysed. Materials and methods Physician-assessed toxicity, using the LENT SOMA scale, and photographs, analysed with the BCCT.core software, was examined for 150 patients, randomized between SIB and sequential boost (SEB). Results Differences in physician-assessed two-years toxicity and photographic ...
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#1Hans Van Hulle (UGent: Ghent University)H-Index: 2
#2Vincent Vakaet (UGent: Ghent University)H-Index: 2
Last. Liv Veldeman (UGent: Ghent University)H-Index: 15
view all 14 authors...
Abstract Introduction Acceleration of radiotherapy in 5 fractions for breast cancer can reduce the burden of treatment. We report on acute toxicity after whole-breast irradiation with a simultaneous integrated boost in 5 fractions over 10-12 days. Material and methods Acute toxicity and health-related quality of life (HRQoL) of 200 patients, randomized between a 15- or 5-fractions schedule, were collected, using the CTCAE toxicity scoring system, the Multidimensional Fatigue Inventory, EORTC QLQ...
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#1Vincent Vakaet (Ghent University Hospital)H-Index: 2
#2Hans Van Hulle (UGent: Ghent University)H-Index: 2
Last. Liv Veldeman (Ghent University Hospital)H-Index: 15
view all 12 authors...
Abstract Introduction Prone position for whole breast irradiation (WBI) results in lower rates of toxicity and reduced ipsilateral mean lung and heart doses. No randomized trials comparing toxicity and cosmesis at 5 years, comparing prone and supine positioning, are available. Methods In this phase II open-label trial, one-hunderd patients, with large breast size requiring WBI were randomized between prone and supine position. Physician-assessed toxicity (retraction, fibrosis, edema, telangiecta...
1 CitationsSource
#1Cedric Peters (Ghent University Hospital)
#2Julie Vandewiele (Ghent University Hospital)
Last. Piet Ost (Ghent University Hospital)H-Index: 41
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Abstract Background Single-fraction radiotherapy (SFRT) offers equal pain relief for uncomplicated painful bone metastases as compared to multiple-fraction radiotherapy (MFRT). Despite this evidence, the adoption of SFRT has been poor with published rates of SFRT for uncomplicated bone metastases ranging from Materials and methods We performed a retrospective review of fractionation schedules at our centre for painful uncomplicated bone metastases from January 2013 until December 2017. Only pati...
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#1Michael E. J. Stouthandel (UGent: Ghent University)H-Index: 2
#2Liv Veldeman (UGent: Ghent University)H-Index: 15
Last. Tom Van Hoof (UGent: Ghent University)H-Index: 16
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#1Michael E. J. Stouthandel (UGent: Ghent University)H-Index: 2
#2Charlotte Debbaut (UGent: Ghent University)H-Index: 11
Last. Tom Van Hoof (UGent: Ghent University)H-Index: 16
view all 6 authors...
Abstract Background Visualizing the lymphatic system and recording the spatial relations between the subclavian lymphatic trunk (SLT) and the surrounding anatomical structures will improve radiotherapy treatment planning for breast cancer patients with lymphatic involvement. An experimental approach to retrogradely fill the SLT with contrast agent was explored. Methods Six Thiel embalmed specimens were bilaterally dissected in the cervical and clavicular region to optimise the new experimental a...
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#1Tim Rattay (University of Leicester)H-Index: 9
#2Petra Seibold (DKFZ: German Cancer Research Center)H-Index: 27
Last. Sheryl GreenH-Index: 18
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Background: Acute skin toxicity is a common and usually transient side-effect of breast radiotherapy although, if sufficiently severe, it can affect breast cosmesis, aftercare costs and the patient's quality-of-life. The aim of this study was to develop predictive models for acute skin toxicity using published risk factors and externally validate the models in patients recruited into the prospective multi-center REQUITE (validating pREdictive models and biomarkers of radiotherapy toxicity to red...
1 CitationsSource