Mustafa Suker
Erasmus University Medical Center
CancerInternal medicineRadiologySurgeryOncologyRetrospective cohort studyRandomized controlled trialIntensive care medicineClinical endpointSarcopeniaChemotherapyFOLFIRINOXPancreasPancreatic cancerStereotactic radiotherapyBorderline resectableIn patientPreoperative chemoradiotherapyLocally advanced pancreatic cancerRadiation therapyClinical trialMedicineGastroenterologyMeta-analysis
Publications 53
#1Maarten Korrel (UvA: University of Amsterdam)H-Index: 4
#2Anne Roelofs (UvA: University of Amsterdam)
Last. Martijn G.H. van Oijen (UvA: University of Amsterdam)H-Index: 37
view all 29 authors...
BACKGROUND Minimally invasive distal pancreatectomy (MIDP) shortens time to functional recovery and improves 30-day quality of life (QoL), as compared with open distal pancreatectomy (ODP) for nonmalignant disease. The impact of MIDP on QoL, cosmetic satisfaction, and overall major complications beyond 1-year follow-up is currently unknown. STUDY DESIGN The Minimally Invasive Versus Open Distal Pancreatectomy (LEOPARD) trial randomized 108 patients to MIDP (laparoscopic or robotic) or ODP in 14 ...
4016Background: Preoperative chemoradiotherapy (CRT) may improve overall survival in resectable pancreatic cancer (RPC) and borderline resectable pancreatic cancer (BRPC). Long term results are pre...
5 CitationsSource
#1Marin Strijker (UvA: University of Amsterdam)H-Index: 8
#2Fleur van der Sijde (EUR: Erasmus University Rotterdam)H-Index: 3
Last. Maarten F. BijlsmaH-Index: 17
view all 23 authors...
Abstract Background We evaluated the stroma marker A Disintegrin And Metalloprotease 12 (ADAM12) as a preoperative prognostic and treatment-predictive marker for overall survival (OS) in pancreatic ductal adenocarcinoma (PDAC) and periampullary cancers. Methods Materials were derived from the prospective nationwide Dutch Pancreas Biobank (2015-2017). We included patients who underwent resection because of PDAC/periampullary cancer or non-invasive IPMN (control group) and had a preoperative serum...
1 CitationsSource
#1M.A. Teriaca (UniFI: University of Florence)
#2Mauro Loi (UniFI: University of Florence)H-Index: 13
Last. Joost J. Nuyttens (EUR: Erasmus University Rotterdam)H-Index: 29
view all 6 authors...
Abstract Purpose: To report the long-term outcome of a multicenter phase II study with FOLFIRINOX followed by stereotactic body radiotherapy (LAPC-1 trial) in patients with locally advanced pancreatic cancer (LAPC). Materials and methods: Patients with histological confirmation of LAPC inoperable at diagnosis were enrolled. Induction therapy with 8 cycles of FOLFIRINOX was administered. If no disease progression was found after chemotherapy, patients received stereotactic body radiotherapy (SBRT...
3 CitationsSource
#1Diba LatifiH-Index: 1
#2Frederieke GreversH-Index: 1
Last. Dana A. M. MustafaH-Index: 4
view all 8 authors...
#1J. Van DongenH-Index: 1
#2Eva VersteijneH-Index: 11
Last. C.H.J. van EijckH-Index: 30
view all 9 authors...
#1Eva Versteijne (UvA: University of Amsterdam)H-Index: 11
#2Mustafa Suker (EUR: Erasmus University Rotterdam)H-Index: 12
Last. Geertjan van Tienhoven (UvA: University of Amsterdam)H-Index: 35
view all 14 authors...
Objectives To investigate the accrual proportion and patients' reasons for not participating in the PREOPANC trial on neoadjuvant chemoradiotherapy vs. immediate surgery in resectable and borderline resectable pancreatic cancer, and to compare these patients' outcomes with those of patients who had been randomized in the trial. Summary of background data The external validity of multicenter randomized trials in cancer treatment has been criticized for suboptimal non-representative inclusion. In ...
1 CitationsSource
#1Jelle C van Dongen (EUR: Erasmus University Rotterdam)H-Index: 2
#2Mustafa Suker (EUR: Erasmus University Rotterdam)H-Index: 12
Last. Casper H.J. van Eijck (EUR: Erasmus University Rotterdam)H-Index: 72
view all 16 authors...
Objectives To investigate the effect of preoperative chemoradiotherapy on surgical complications in patients after pancreatic resection for (borderline-)resectable pancreatic cancer. Summary of background data Preoperative chemoradiotherapy is increasingly used in patients with (borderline-)resectable pancreatic cancer. Concerns have been raised about the potential harmful effect of any preoperative therapy on the surgical complication rate after pancreatic resection. Methods An observational an...
6 CitationsSource
#1Joost J. NuyttensH-Index: 29
#2Mustafa SukerH-Index: 12
Last. C.H.J. van EijckH-Index: 30
view all 4 authors...
#1Remy Klaassen (UvA: University of Amsterdam)H-Index: 12
#2Anne Steins (UvA: University of Amsterdam)H-Index: 6
Last. Hanneke W. M. van Laarhoven (UvA: University of Amsterdam)H-Index: 40
view all 18 authors...
Patient stratification based on biological variation in pancreatic ductal adenocarcinoma (PDAC) subtypes could help to improve clinical outcome. However, non-invasive assessment of the entire tumor microenvironment remains challenging. In this study we investigate the biological basis of dynamic contrast-enhanced (DCE), intravoxel incoherent motion (IVIM) and R2* derived Magnetic Resonance Imaging (MRI) parameters for the non-invasive characterization of the PDAC tumor microenvironment and evalu...
9 CitationsSource