Sylvane Desrivières
King's College London
GeneGenome-wide association studyPsychopathologyInternal medicineEndocrinologyDevelopmental psychologyPsychologyNeuroscienceCognitionFunctional magnetic resonance imagingImpulsivityAttention deficit hyperactivity disorderAlcoholPopulationAddictionGeneticsNeuroimagingClinical psychologyMedicineCohortBiology
Publications 185
#1Roxanna Korologou-Linden (UoB: University of Bristol)H-Index: 7
#2B. Xu (EUR: Erasmus University Rotterdam)
Last. Emma L Anderson (UoB: University of Bristol)H-Index: 19
view all 38 authors...
Neuropathological changes associated with Alzheimers disease (AD) can occur decades before clinical symptoms. We investigated whether neurodevelopment and/or neurodegeneration affects the risk of AD, through reducing structural brain reserve and/or accelerating brain atrophy, respectively. We used bidirectional two-sample Mendelian randomization to estimate the effects of genetic liability to AD on global and regional cortical thickness, total intracranial volume, volume of subcortical structure...
#1Yi Zhang (University of Cambridge)
#2Qiang Luo (Fudan University)H-Index: 16
Last. Jianfeng FengH-Index: 53
view all 31 authors...
Psychological androgyny has long been associated with greater cognitive flexibility, adaptive behavior, and better mental health, but whether a similar concept can be defined using neural features remains unknown. Using the neuroimaging data from 9620 participants, we found that global functional connectivity was stronger in the male brain before middle age but became weaker after that, when compared with the female brain, after systematic testing of potentially confounding effects. We defined a...
#1Laurent Elkrief (UdeM: Université de Montréal)H-Index: 2
#2Sean Spinney (UdeM: Université de Montréal)H-Index: 1
Last. Patricia J. Conrod (UdeM: Université de Montréal)H-Index: 67
view all 28 authors...
Genetic markers of endocannabinoid system have been linked to a variety of addiction-related behaviours that extend beyond cannabis use. In the current study we investigate the relationship between eCB genetic markers and AUDs in European adolescents (14-18 years old), followed in the IMAGEN study (n=2051) and explore replication in a cohort of North American adolescents from Canadian Saguenay Youth Study (SYS) (n=772). Case-Control status is represented by a score of more than 7 on the Alcohol ...
#1Boris William Böttinger (Heidelberg University)H-Index: 1
#3Sarah Baumeister (Heidelberg University)H-Index: 18
Last. Frauke Nees (Heidelberg University)H-Index: 34
view all 29 authors...
Conduct problems (CP) in patients with disruptive behavior disorders have been linked to impaired prefrontal processing of negative facial affect compared to controls. However, it is unknown whether associations with prefrontal activity during affective face processing hold along the CP dimension in a healthy population sample, and how subcortical processing is affected. We measured functional brain responses during negative affective face processing in 1444 healthy adolescents [M = 14.39 years ...
#1Haiyan Wang (CAS: Chinese Academy of Sciences)H-Index: 2
#2Lingzhong Fan (CAS: Chinese Academy of Sciences)H-Index: 25
Last. Tianzi Jiang (CAS: Chinese Academy of Sciences)H-Index: 88
view all 32 authors...
Derailment of inhibitory control (IC) underlies numerous psychiatric and behavioral disorders, many of which emerge during adolescence. Identifying reliable predictive biomarkers that place the adolescents at elevated risk for future IC deficits can help guide early interventions, yet the scarcity of longitudinal research has hindered the progress. Here, using a large-scale longitudinal dataset in which the same subjects performed a stop signal task during functional magnetic resonance imaging a...
#1Francesca Biondo ('KCL': King's College London)H-Index: 4
#2Charlotte Nymberg Thunell ('KCL': King's College London)H-Index: 1
Last. Gunter Schumann ('KCL': King's College London)H-Index: 68
view all 30 authors...
BACKGROUND Sex-related differences in psychopathology are known phenomena, with externalizing and internalizing symptoms typically more common in boys and girls, respectively. However, the neural correlates of these sex-by-psychopathology interactions are underinvestigated, particularly in adolescence. METHODS Participants were 14 years of age and part of the IMAGEN study, a large (N = 1526) community-based sample. To test for sex-by-psychopathology interactions in structural grey matter volume ...
#1Irina Filippi ('ENS Paris': École Normale Supérieure)H-Index: 3
#1Irina Filippi ('ENS Paris': École Normale Supérieure)
Last. Jean-Luc Martinot ('ENS Paris': École Normale Supérieure)H-Index: 52
view all 35 authors...
Early initiation of polysubstance use (PSU) is a strong predictor of subsequent addiction, however scarce individuals present resilience capacity. This neuroimaging study aimed to investigate structural correlates associated with cessation or reduction of PSU and determine the extent to which brain structural features accounted for this resilient outcome. Participants from a European community-based cohort self-reported their alcohol, tobacco and cannabis use frequency at ages 14, 16 and 19 and ...
#1Ida E Sønderby (University of Oslo)H-Index: 14
#3Dennis van der Meer (UM: Maastricht University)H-Index: 20
Last. Ole A. Andreassen (Oslo University Hospital)H-Index: 125
view all 144 authors...
Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders, including schizophrenia, autism and intellectual disability. Human carriers display a high prevalence of micro- and macrocephaly in deletion and duplication carriers, respectively. The underlying brain structural diversity remains largely unknown. We systematically called CNVs in 38 cohorts from the large-scale ENIGMA-CNV collaboration and the UK Bioba...
1 CitationsSource
#1Yara J. Toenders (University of Melbourne)H-Index: 3
#2Akhil Kottaram (University of Melbourne)H-Index: 3
Last. Lianne Schmaal (University of Melbourne)H-Index: 34
view all 34 authors...
Abstract Background Adolescent onset of depression is associated with long-lasting negative consequences. Identifying adolescents at risk for developing depression would enable the monitoring of risk-factors and the development of early intervention strategies. Using machine learning to combine several risk factors from multiple modalities might allow prediction of depression onset at the individual level. Methods A subsample of a multi-site longitudinal study in adolescents, the IMAGEN study, w...
#1Mira Tschorn (University of Potsdam)
#1M. Tschorn (University of Potsdam)H-Index: 1
Last. Michael A. Rapp (University of Potsdam)H-Index: 38
view all 26 authors...
Traditional models of future alcohol use in adolescents have used variable-centered approaches, predicting alcohol use from a set of variables across entire samples or populations. Following the proposition that predictive factors may vary in adolescents as a function of family history, we used a two-pronged approach by first defining clusters of familial risk, followed by prediction analyses within each cluster. Thus, for the first time in adolescents, we tested whether adolescents with a famil...