Klaus Kaier
University of Freiburg
Internal medicineSurgeryOdds ratioCardiologyRetrospective cohort studyIntensive care medicinePediatricsEmergency medicineAortic valve replacementMechanical ventilationSubarachnoid hemorrhageValve replacementAortic valve stenosisTranscatheter aorticIncidence (epidemiology)AntibioticsStrokeMedicineCohortAntibiotic resistance
166Publications
21H-index
1,454Citations
Publications 172
Newest
#1Peter Stachon (University of Freiburg)H-Index: 18
#2Klaus Kaier (University Medical Center Freiburg)H-Index: 21
Last. Constantin von zur Mühlen (University of Freiburg)H-Index: 24
view all 7 authors...
Abstract Background If the transfemoral access is not feasible, a transapical access or surgical aortic valve replacement are alternatives for patients with aortic valve stenosis. Objectives In order to identify patient groups who benefit from SAVR or TA-TAVR, we compared in-hospital outcomes of patients in a nationwide data-set. Methods We identified 19,016 isolated SAVR and 6,432 TA-TAVR performed in Germany 2014 - 2016. We adjusted for risk factors using a covariate- and propensity-adjusted a...
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#1Markus Jäckel (University of Freiburg)H-Index: 4
#2Klaus Kaier (University of Freiburg)H-Index: 21
Last. Christoph Bode (University of Freiburg)H-Index: 74
view all 12 authors...
ABSTRACT Presentation and mortality of coronary artery disease (CAD) substantially differs in both sexes. Most of the existing data analyzing sex differences is older than 10 years and mostly was retrieved in clinical trials, which are potentially structured with a bias against the inclusion of women, leading to a potential selection-bias. Meanwhile, with better diagnostic and therapeutic options, actual data analyzing sex differences in emergency CAD patients is rare.Data on all emergency case ...
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#1Peter Stachon (University of Freiburg)H-Index: 18
#2Philip Hehn (University of Freiburg)H-Index: 8
Last. Klaus Kaier (University of Freiburg)H-Index: 21
view all 9 authors...
The effect of valve type on outcomes in transfemoral transcatheter aortic valve replacement (TF-TAVR) has recently been subject of debate. We investigate outcomes of patients treated with balloon-expanding (BE) vs. self-expanding (SE) valves in in a cohort of all these procedures performed in Germany in 2018. All patients receiving TF-TAVR with either BE (N = 9,882) or SE (N = 7,413) valves in Germany in 2018 were identified. In-hospital outcomes were analyzed for the endpoints in-hospital morta...
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#1Marina Rieder (University of Freiburg)H-Index: 6
#2Nadine Gauchel (University of Freiburg)H-Index: 1
Last. Maria Rüthrich (Leibniz Association)H-Index: 4
view all 18 authors...
Coagulopathy and venous thromboembolism are common findings in coronavirus disease 2019 (COVID-19) and are associated with poor outcome. Timely initiation of anticoagulation after hospital admission was shown to be beneficial. In this study we aim to examine the association of pre-existing oral anticoagulation (OAC) with outcome among a cohort of SARS-CoV-2 infected patients. We analysed the data from the large multi-national Lean European Open Survey on SARS-CoV-2 infected patients (LEOSS) from...
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#1Jan Wolff (MHH: Hannover Medical School)H-Index: 10
#2Gudrun HefnerH-Index: 11
Last. Ansgar Klimke (HHU: University of Düsseldorf)H-Index: 24
view all 10 authors...
PURPOSE The aim of this study was to analyse the epidemiology of polypharmacy in hospital psychiatry. Another aim was to investigate predictors of the number of drugs taken and the associated risks of drug-drug interactions and potentially inappropriate medications in the elderly. METHODS Daily prescription data were obtained from a pharmacovigilance project sponsored by the Innovations Funds of the German Federal Joint Committee. RESULTS The study included 47 071 inpatient hospital cases from 8...
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#1Corinna N. Lang (University of Freiburg)H-Index: 10
#2Klaus Kaier (University of Freiburg)H-Index: 21
Last. Dawid L. Staudacher (University of Freiburg)H-Index: 14
view all 12 authors...
A central element in the management of cardiogenic shock (CS) comprises mechanical circulatory support (MCS) systems to maintain cardiac output (CO). This study aims to quantify incidence, outcome and influence of MCS in CS over the last decade. All patients hospitalized with CS in a tertiary university hospital in Germany between 2007 and 2017 were identified utilizing the international coding system ICD-10 with code R57.0. Application of MCS was identified via German procedure classification c...
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#1Peter Stachon (University of Freiburg)H-Index: 18
#2Klaus Kaier (University of Freiburg)H-Index: 21
Last. Manfred Zehender (University of Freiburg)H-Index: 31
view all 12 authors...
BACKGROUND Recent randomized controlled trials have sparked debate about the optimal treatment of patients suffering from left main coronary artery disease. The present study analyzes outcomes of left main stenting versus coronary bypass grafting (CABG) in a nationwide registry in patients with chronic coronary syndrome (CCS). METHODS All cases suffering from CCS and left main coronary artery disease treated either with CABG or stent, were identified within the database of the German bureau of s...
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#1Katrin RothH-Index: 1
#2Klaus KaierH-Index: 21
Last. I Juhasz-BössH-Index: 4
view all 7 authors...
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#1Ramazan Jabbarli (University of Duisburg-Essen)H-Index: 15
#2Yahya Ahmadipour (University of Duisburg-Essen)H-Index: 8
Last. Nika Guberina (University of Duisburg-Essen)H-Index: 10
view all 15 authors...
Despite multimodal treatment, the prognosis of patients with glioblastoma (GBM) remains poor. Previous studies showed conflicting results on the effect of antiepileptic drugs (AED) on GBM survival. We investigated the associations of different AED with overall survival (OS) and progression-free survival (PFS) in a large institutional GBM cohort (n = 872) treated January 2006 and December 2018. In addition, we performed a meta-analysis of previously published studies, including this study, to sum...
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#1Hanna Renk (Boston Children's Hospital)H-Index: 8
#2Alex Dulovic (University of Tübingen)H-Index: 5
Last. Sebastian Bode (University of Ulm)H-Index: 2
view all 47 authors...
Abstract null Background null Long-term persistence of antibodies against SARS-CoV-2, particularly the SARS-CoV-2 Spike Trimer, determines individual protection against infection and potentially viral spread. The quality of children’s natural humoral immune response following SARS-CoV-2 infection is yet incompletely understood but crucial to guide pediatric SARS-CoV-2 vaccination programs. null Methods null In this prospective observational multi-center cohort study, we followed 328 households, ...
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