Rossella Elisei
University of Pisa
CancerEndocrinologySurgeryPathologyOncologyLenvatinibThyroidectomyCarcinomaThyroglobulinThyroid nodulesCalcitoninThyroid cancerMedullary thyroid cancerPapillary thyroid cancerThyroid carcinomaCancer researchThyroidMedicineBiologyGastroenterology
Publications 313
Last. Francesco LatrofaH-Index: 21
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#1Antonio Matrone (UniPi: University of Pisa)H-Index: 10
#2Carla Gambale (UniPi: University of Pisa)H-Index: 2
Last. Rossella Elisei (UniPi: University of Pisa)H-Index: 68
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OBJECTIVE Recently, several scientific societies designed ultrasound (US) risk stratification systems (RSS) to guide the work-up of thyroid nodules and decide which nodules should undergo fine needle aspiration cytology (FNAC). However, these systems have been developed against papillary thyroid carcinoma, and scanty data on their role in identifying medullary thyroid carcinoma (MTC) are available. The aims of this study are to describe the US features of MTC and evaluate the performance of RSS ...
#1Eleonora Molinaro (UniPi: University of Pisa)H-Index: 35
#2Maria Cristina Campopiano (UniPi: University of Pisa)H-Index: 5
Last. Rossella Elisei (UniPi: University of Pisa)H-Index: 68
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In the last decades, the incidence of thyroid cancer (TC) has more than doubled, but the disease-specific mortality rate was stable. To date 30-40% of all TC is represented by papillary microcarcinomas (mPTC), an indolent tumor, that probably remained undiagnosed before routine ultrasound use. In 1993, Miyauchi was the first who hypothesized a conservative approach for low-risk mPTC and introduced the concept of active surveillance (AS) in its clinical management. The progression rate of mPTC du...
Introduction [18F]-FDG-PET/CT positive metastatic lesions in radioiodine-refractory differentiated thyroid cancer (RAI-R DTC) have a poor prognosis and lenvatinib represents the best therapy. We investigated the role of [ 18F]-FDG-PET/CT in the evaluation of metabolic response and prediction of the outcome of RAI-R DTC patients treated with lenvatinib. Materials and methods Thirty-three progressive metastatic RAI-R DTC patients treated with lenvatinib were investigated at baseline and during fol...
#1Seza A. GulecH-Index: 29
#2Sukhjeet Ahuja (Society of Nuclear Medicine and Molecular Imaging)H-Index: 4
Last. R. M. Tuttle (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 15
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BACKGROUND The American Thyroid Association, the European Association of Nuclear Medicine, the European Thyroid Association and the Society of Nuclear Medicine and Molecular Imaging have established an inter-societal working group to address the current controversies and evolving concepts in thyroid cancer management and therapy. The working group annually identifies topics that may significantly impact clinical practice and publishes expert opinion papers reflecting inter-societal collaboration...
Differentiated thyroid cancers (DTC) are commonly and successfully treated with total thyroidectomy plus/minus radioiodine therapy (RAI). Medullary thyroid cancer (MTC) is only treated with surgery but only intrathyroidal tumors are cured. The worst prognosis is for anaplastic (ATC) and poorly differentiated thyroid cancer (PDTC). Whenever a local or metastatic advanced disease is present, other treatments are required, varying from local to systemic therapies. In the last decade, the efficacy o...
#1Alda Corrado (UniPi: University of Pisa)H-Index: 12
#2Romina AcetoH-Index: 1
Last. Federica Gemignani (UniPi: University of Pisa)H-Index: 35
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#1Alessandro Prete (UniPi: University of Pisa)H-Index: 3
#2Marco Falcone (UniPi: University of Pisa)H-Index: 33
Last. Rossella Elisei (UniPi: University of Pisa)H-Index: 68
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PURPOSE Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is challenging health systems all over the world. Cancer patients have a higher risk of being infected by SARS-Cov-2 and higher coronavirus disease 2019 (COVID-19) severity and mortality. Up to date, there were no data about COVID-19 in patients with thyroid cancer (TCs). The aim of the study was to describe the prevalence of COVID-19 in a well-characterized series of TC patients evaluated for the persistence of the neoplastic ...
#1Matthew H. Taylor (Providence Portland Medical Center)H-Index: 2
#2Shunji TakahashiH-Index: 27
Last. Lori J. Wirth (Harvard University)H-Index: 42
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BACKGROUND Radioiodine-refractory differentiated thyroid cancer (RR-DTC) has a low 10-year patient-survival rate and is challenging to treat. Lenvatinib is a multikinase inhibitor approved for treatment of RR-DTC. This study aims to assess Eastern Cooperative Oncology Group performance status (ECOG PS) and neutrophil-to-lymphocyte ratio (NLR) as prognostic markers for patients with RR-DTC treated with lenvatinib. METHODS In this retrospective analysis of SELECT, patients randomly assigned to rec...