Angelo Zinellu
University of Sassari
AnalyteInternal medicineEndocrinologyChemistryOxidative stressCOPDInflammationDerivatizationHomocysteineCysteineTaurineAsymmetric dimethylarginineCapillary electrophoresisPopulationChromatographyGlutathioneBiochemistryMedicineBiologyGastroenterologyMeta-analysis
279Publications
31H-index
3,211Citations
Publications 277
Newest
#1Maria Carmina Pau (University of Sassari)H-Index: 3
#2Elisabetta ZinelluH-Index: 16
Last. Pietro Pirina (University of Sassari)H-Index: 26
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Oxidative stress induced by nocturnal intermittent hypoxia plays a significant pathophysiological role in obstructive sleep apnea (OSA). Malondialdehyde (MDA), one of the most commonly investigated markers of lipid peroxidation, might assist with the monitoring of oxidative balance in OSA. We conducted a systematic review and meta-analysis to evaluate the differences in circulating MDA concentrations between patients with OSA and non-OSA controls. A systematic search was conducted in the electro...
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#1Angelo Zinellu (University of Sassari)H-Index: 31
#2Salvatore Sotgia (University of Sassari)H-Index: 25
Last. Arduino A. Mangoni (Flinders University)H-Index: 40
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Alterations in cardiac biomarkers have been reported in patients with coronavirus disease 2019 (COVID-19) in relation to disease severity and mortality. We conducted a systematic review and meta-analysis with meta-regression of studies reporting B-type natriuretic peptide (BNP) or N-terminal proBNP (NT-proBNP) plasma concentrations in COVID-19. We searched PubMed, Web of Science, and Scopus, between January 2020 and 2021, for studies reporting BNP/NT-proBNP concentrations, measures of COVID-19 s...
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Abstract null null Background null Anastomotic leakage (AL) is one of the most severe complications in colorectal surgery. Currently, no predictive biomarkers of AL are available. The aim of this study was to investigate the role of C reactive protein (CRP) to albumin ratio (CAR) as a predictor of AL in patients undergoing elective surgery for colorectal cancer. Materials and Methods. Data on 1183 consecutive patients surgically treated for histologically proven colorectal cancer in the surgical...
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#1Caterina Arru (University of Sassari)H-Index: 1
#2Maria Rosaria De Miglio (University of Sassari)H-Index: 22
Last. Panagiotis Paliogiannis (University of Sassari)H-Index: 19
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Introduction null Cancer immunotherapy represents one of the most important innovations in modern medicine. Durvalumab is an anti-programmed cell death ligand 1 (PDL-1) agent which is currently under investigation in several studies in combination with the anti-cytotoxic T lymphocyte-associated protein 4 (CTLA-4) drug tremelimumab. The aim of this review was to systematically identify and revise the current scientific literature investigating the combination of these two drugs in solid tumors. n...
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#1Alessandro G. FoisH-Index: 17
#2Valentina ScanoH-Index: 4
Last. Angelo ZinelluH-Index: 31
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#1Angelo Zinellu (University of Sassari)H-Index: 31
#2Panagiotis Paliogiannis (University of Sassari)H-Index: 19
Last. Arduino A. Mangoni (Flinders Medical Centre)H-Index: 40
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Platelets play an important role in the pathophysiology of chronic obstructive pulmonary disease (COPD) by mediating thrombotic, inflammatory, and immune processes in the lung. We conducted a syste...
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#1Elisabetta ZinelluH-Index: 16
#2Angelo Zinellu (University of Sassari)H-Index: 31
Last. Pietro Pirina (University of Sassari)H-Index: 26
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Background Chronic Obstructive Pulmonary Disease (COPD) is a progressive disease characterized by a not fully reversible airflow limitation associated with an abnormal inflammatory response. Exacerbations of COPD are of major importance in the acceleration of disease progression, in healthcare costs, and negatively affect the patient's quality of life. Exacerbations are characterized by a further increase in the airway inflammation likely driven by oxidative stress. In order to deepen the knowle...
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#1Angelo Zinellu (University of Sassari)H-Index: 31
#2Andrea De Vito (University of Sassari)H-Index: 5
Last. Alessandro G. Fois (University of Sassari)H-Index: 17
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Introduction The early identification of factors that predict the length of hospital stay (HS) in patients affected by coronavirus desease (COVID-19) might assist therapeutic decisions and patient flow management. Methodology We collected, at the time of admission, routine clinical, laboratory, and imaging parameters of hypoxia, lung damage, inflammation, and organ dysfunction in a consecutive series of 50 COVID-19 patients admitted to the Respiratory Disease and Infectious Disease Units of the ...
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#1Antonio Pinna (University of Sassari)H-Index: 9
#2Paola Carlino (University of Sassari)
Last. Angelo Zinellu (University of Sassari)H-Index: 31
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Purpose: To assess the role of complete blood cell count (CBC) dimensional indices and CBC-derived measures in non-arteritic anterior ischemic optic neuropathy (NA-AION). Methods: In this retrospective case-control survey, 37 newly diagnosed NA-AION patients and 37 sex- and age-matched cataract controls were enrolled in 2017-2018. On the same day of NA-AION diagnosis, a blood sample was collected and CBC was determined using an automatic blood counter. CBC dimensional indices, such as mean plate...
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